SCHEMBL4099219

SCHEMBL4099219

OCCNc1ccnnn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 3/20 0.40
GAA P10253 3/20 0.40
POLB P06746 2/20 0.40
MAP4K4 O95819 4/20 0.39
CLK4 Q9HAZ1 4/20 0.39
JAK2 O60674 3/20 0.39
CLK2 P49760 3/20 0.39
DYRK1A Q13627 3/20 0.39
TYK2 P29597 2/20 0.39
ROCK2 O75116 2/20 0.39
GSK3B P49841 2/20 0.39
IL1B P01584 2/20 0.39
TNF P01375 1/20 0.39
NLRP3 Q96P20 1/20 0.39
RPS6KB1 P23443 1/20 0.39
ROCK1 Q13464 1/20 0.39
NUDT1 P36639 1/20 0.39
MAPK1 P28482 3/20 0.37
MINK1 Q8N4C8 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2586175 0.83
SCHEMBL5756006 0.78 IL1B (0.53) KDM4EALDH1A1GAAPOLBMAP4K4
SCHEMBL29046912 0.77 CYP2D6 (0.35) CDK1CYP2D6KDM4DEGFR
Hydrochloric Acid SCHEMBL5756281 0.76 IL1B (0.51) KDM4EALDH1A1GAAPOLBMAP4K4
SCHEMBL5757740 0.76 GOT1 (0.50) KDM4EALDH1A1GAAPOLBMAP4K4
SCHEMBL514929 0.76 TLR8 (0.46) LMNASMN1; SMN2
SCHEMBL5845138 0.75
SCHEMBL28859627 0.74 DNM2 (0.47) LMNASMN1; SMN2
SCHEMBL3689385 0.74 DNM2 (0.47) LMNASMN1; SMN2
SCHEMBL27736222 0.72 GOT1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0200906-A2 Modified melamine resin, its fabrication, its use and the modification agent CASSELLA Aktiengesellschaft (DE) 1986-11-12 EP claimed
US-20090099323-A1 Melamine-formaldehyde resin solution and process for producing the same AMI-AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2009-04-16 US disclosed
CN-101175782-A Melamine-formaldehyde resin solution and process for producing the same AMI AGROLINZ MELAMINE INT GMBH (AT) 2008-05-07 CN disclosed
EP-1879935-A1 MELAMINE-FORMALDEHYDE RESIN SOLUTION AND PROCESS FOR PRODUCING THE SAME AMI Agrolinz Melamine International GmbH (AT) 2008-01-23 EP disclosed
WO-2006119982-A1 MELAMINE-FORMALDEHYDE RESIN SOLUTION AND PROCESS FOR PRODUCING THE SAME AMI AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2006-11-16 WO disclosed
EP-0200906-A3 MODIFIED MELAMINE RESIN, ITS FABRICATION, ITS USE AND THE MODIFICATION AGENT CASSELLA Aktiengesellschaft (DE) 1988-06-15 EP disclosed
EP-0200906-A2 Modified melamine resin, its fabrication, its use and the modification agent CASSELLA Aktiengesellschaft (DE) 1986-11-12 EP disclosed
EP-0200906-A2 Modified melamine resin, its fabrication, its use and the modification agent CASSELLA Aktiengesellschaft (DE) 1986-11-12 EP disclosed