Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875136 | 1.00 | PTGES (0.58) | PTGESALOX5PPARGSCN9A | |
| SCHEMBL8875155 | 1.00 | PTGES (0.58) | PTGESALOX5PPARGSCN9A | |
| SCHEMBL421658 | 0.88 | BCHE (0.56) | — | |
| SCHEMBL8874672 | 0.88 | BCHE (0.56) | — | |
| SCHEMBL421657 | 0.88 | BCHE (0.56) | — | |
| Hydrochloric Acid SCHEMBL23780699 | 0.87 | KDM4E (0.56) | — | |
| Hydrochloric Acid SCHEMBL23780698 | 0.87 | KDM4E (0.56) | — | |
| SCHEMBL17773509 | 0.85 | PPARG (0.52) | PTGESALOX5PPARG | |
| SCHEMBL18342645 | 0.83 | ALPI (0.54) | PTGESALOX5PPARG | |
| SCHEMBL7375715 | 0.83 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | disclosed |