Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743226 | 1.00 | MAPT (0.57) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL10654380 | 0.86 | KMT2A (0.53) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL8552964 | 0.83 | RAB9A (0.49) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL28351808 | 0.82 | PTGS2 (0.48) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL18005443 | 0.82 | PTGS2 (0.48) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL8168071 | 0.82 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL7872685 | 0.82 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL9252387 | 0.81 | RAB9A (0.67) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL9347743 | 0.81 | RAB9A (0.67) | MAPTRAB9ANPC1SMN1; SMN2STAT3 | |
| SCHEMBL7090931 | 0.81 | RAB9A (0.67) | MAPTRAB9ANPC1SMN1; SMN2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641428-A | SHORT SWITCHING TIMES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5380460-A | Ferroelectric liquid crystal compounds containing chiral haloalkoxy tail units and compositions containing them | DISPLAYTECH, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0295370-B1 | LIQUID-CRYSTALLINE 5-PHENYL PYRIMIDINE DERIVATIVES WITH AN SC OR SC (ASTERISK) PHASE, AND METHOD FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| WO-1993006192-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOUNDS CONTAINING CHIRAL HALOALKOXY TAIL UNITS AND COMPOSITIONS CONTAINING THEM | DISPLAYTECH, INCORPORATED (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0288813-B1 | USE OF OPTICALLY ACTIVE 1,3-DIOXOLANE-4-CARBOXYLIC-ACID ESTERS AS DOPING AGENTS IN LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |
| US-4906752-A | Liquid-crystal 5-phenylpyrimidine derivatives having sc or sc* phases and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |
| EP-0288813-A1 | Use of optically active 1,3-dioxolane-4-carboxylic-acid esters as doping agents in liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-02 | — | — | EP | disclosed |