Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876471 | 0.88 | KMT2A (0.49) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8876339 | 0.85 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2DPP4ALDH1A1 | |
| SCHEMBL8874935 | 0.82 | SMN1; SMN2 (0.34) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8318132 | 0.81 | ABCB1 (0.33) | KMT2AMEN1SMN1; SMN2GAAABCB1 | |
| SCHEMBL8876430 | 0.81 | KMT2A (0.38) | KMT2AMEN1SMN1; SMN2GAAABCB1 | |
| SCHEMBL8879187 | 0.80 | KMT2A (0.38) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8876270 | 0.79 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2GAAABCB1 | |
| SCHEMBL8983644 | 0.76 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8875822 | 0.75 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8875764 | 0.75 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |