Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875458 | 0.88 | KMT2A (0.37) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8879187 | 0.88 | KMT2A (0.38) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8316663 | 0.81 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8875882 | 0.81 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8876339 | 0.80 | KMT2A (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1KDM4E | |
| SCHEMBL8874935 | 0.80 | SMN1; SMN2 (0.34) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8879041 | 0.79 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8876904 | 0.77 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8877073 | 0.76 | KMT2A (0.55) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8875666 | 0.75 | KMT2A (0.52) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |