Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875458 | 0.85 | KMT2A (0.37) | KMT2ASMN1; SMN2DPP4ALDH1A1MEN1 | |
| SCHEMBL8875634 | 0.82 | KMT2A (0.42) | KMT2ALMNASMN1; SMN2DPP4CYP3A4 | |
| SCHEMBL8318325 | 0.82 | KMT2A (0.39) | KMT2ALMNASMN1; SMN2DPP4CYP3A4 | |
| SCHEMBL8875491 | 0.81 | SMN1; SMN2 (0.40) | KMT2ALMNASMN1; SMN2CYP2C9TDP1 | |
| SCHEMBL8876471 | 0.80 | KMT2A (0.49) | KMT2ALMNASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL8876722 | 0.80 | TSHR (0.44) | KMT2ALMNASMN1; SMN2DPP4CYP3A4 | |
| SCHEMBL8877083 | 0.79 | TSHR (0.45) | KMT2ATSHRERCC1ERCC4SIGMAR1 | |
| SCHEMBL8877609 | 0.78 | KMT2A (0.44) | KMT2ATSHRERCC1ERCC4SIGMAR1 | |
| SCHEMBL8876049 | 0.77 | TSHR (0.48) | KMT2ASMN1; SMN2TSHRSIGMAR1ALDH1A1 | |
| SCHEMBL8875758 | 0.77 | TSHR (0.41) | KMT2ALMNASMN1; SMN2DPP4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |