Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775652 | 0.91 | HTT (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL7775648 | 0.91 | HTT (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL20530448 | 0.88 | LMNA (0.55) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL20530450 | 0.85 | LMNA (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL8877816 | 0.84 | SLC1A3 (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL735078 | 0.83 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL734427 | 0.83 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL590358 | 0.83 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL18667866 | 0.82 | LMNA (0.60) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL3701581 | 0.82 | LMNA (0.60) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8198832-A | — | — | None | — | — | JP | disclosed |
| US-5599954-A | N-substituted-7-amino-5-hydroxy-3-oxoheptanoic acid derivatives and method for producing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1997-02-04 | — | — | US | disclosed |
| JP-H08198832-A | N-SUBSTITUTED-7-AMINO-5-HYDROXY-3-OXOHEPTANOIC ACID DERIVATIVE AND ITS PRODUCTION | TAKASAGO INTERNATL CORP | 1996-08-06 | — | — | JP | disclosed |