Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775648 | 1.00 | HTT (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL8877816 | 0.93 | SLC1A3 (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL9772192 | 0.91 | HTT (0.64) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| SCHEMBL8875950 | 0.91 | HTT (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL9772191 | 0.91 | HTT (0.64) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| SCHEMBL20530450 | 0.89 | LMNA (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL735078 | 0.87 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL590358 | 0.87 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL734427 | 0.87 | LMNA (0.61) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL20530448 | 0.87 | LMNA (0.55) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737751-B1 | Method for producing optically active ester of gamma-substituted-beta-hydroxybutyric acid | MITSUBISHI CHEM CORP (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-5700670-A | TREATING MICROORGANISM CULTURE WITH ALKYL ESTER OF GAMMA-SUBSTITUTED ACETOACETIC ACID FOR STEREOSPECIFIC REDUCTION OF CARBONYL GROUP TO HYDROXYL GROUP YIELDS GAMMA-SUBSTITUTED 3-HYDROXYBUTYRIC ACID | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0737751-A2 | Method for producing optically active ester of gamma-substituted-beta-hydroxybutyric acid | Mitsubishi Chemical Corporation (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |