Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874051 | 0.81 | PPARA (0.44) | PPARASIRT2TNKS2HDAC6ALDH1A1 | |
| SCHEMBL1220695 | 0.80 | PPARA (0.52) | PPARAHSP90AA1HSP90AB1CA2CA1 | |
| SCHEMBL25801692 | 0.79 | PPARA (0.54) | PPARAHSP90AA1HSP90AB1CA2CA1 | |
| SCHEMBL26659534 | 0.77 | HSP90AA1 (0.34) | PPARAHSP90AA1HSP90AB1 | |
| SCHEMBL8874619 | 0.77 | PPARA (0.40) | PPARASIRT2TNKS2HSP90AA1HSP90AB1 | |
| SCHEMBL18255995 | 0.75 | HSP90AA1 (0.38) | PPARAHSP90AA1HSP90AB1 | |
| SCHEMBL8874885 | 0.71 | ALDH1A1 (0.44) | SIRT2HDAC6ALDH1A1CYP1A2 | |
| SCHEMBL18255943 | 0.70 | NR1I2 (0.43) | PPARAHDAC6ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL18256140 | 0.70 | PPARA (0.37) | PPARAALDH1A1 | |
| SCHEMBL1087387 | 0.69 | MAPT (0.40) | HSP90AA1HSP90AB1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |