Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104968 | 0.80 | TDP1 (0.37) | GAAMAPK1TDP1L3MBTL1CA12 | |
| SCHEMBL4805183 | 0.79 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL952515 | 0.78 | KEAP1 (0.45) | GAAMAPK1CA12CA1CA2 | |
| SCHEMBL11590899 | 0.77 | CA12 (0.66) | GAAMAPK1TDP1L3MBTL1CA12 | |
| SCHEMBL15952072 | 0.77 | GAA (0.63) | GAAMAPK1TDP1L3MBTL1CA12 | |
| SCHEMBL26317210 | 0.75 | MEN1 (0.40) | GAATDP1CA1CA2CA9 | |
| SCHEMBL8623279 | 0.74 | TDP1 (0.50) | MAPK1TDP1CA12CA1CA2 | |
| SCHEMBL4538720 | 0.74 | PLCG1 (0.45) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL4119819 | 0.73 | TDP1 (0.48) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL8876368 | 0.73 | CA12 (0.51) | GAAMAPK1TDP1L3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430994-A | Compound, composition and method for adjusting CFTR | 蛋白质平衡治疗股份有限公司 | 2018-08-21 | — | — | CN | disclosed |
| EP-0792307-A1 | POLYMERIZABLE COMPOSITION AND PROCESS FOR POLYMERIZING CYCLICAL OLEFINS | Ciba SC Holding AG (CH) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996016103-A1 | POLYMERIZABLE COMPOSITION AND PROCESS FOR POLYMERIZING CYCLICAL OLEFINS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1996-05-30 | — | — | WO | disclosed |