Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878869 | 0.93 | POLB (0.43) | MDM2POLBNPC1RAB9ATSHR | |
| SCHEMBL8875891 | 0.85 | POLB (0.41) | MDM2POLBTSHRKDM4EALDH1A1 | |
| SCHEMBL8877501 | 0.82 | MDM2 (0.39) | MDM2POLBNPC1RAB9ATSHR | |
| SCHEMBL8877609 | 0.82 | KMT2A (0.44) | POLBRAB9ATSHRALDH1A1MEN1 | |
| SCHEMBL8314698 | 0.82 | SMN1; SMN2 (0.35) | MDM2POLBNPC1RAB9ATSHR | |
| SCHEMBL8874706 | 0.80 | KMT2A (0.44) | POLBTSHRKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL8876228 | 0.80 | SMN1; SMN2 (0.39) | MDM2POLBNPC1RAB9AKDM4E | |
| SCHEMBL9727473 | 0.80 | FKBP1A (0.47) | POLBTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL8877150 | 0.79 | POLB (0.39) | MDM2POLBNPC1RAB9ATSHR | |
| SCHEMBL8878180 | 0.78 | POLB (0.40) | POLBTSHRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |