Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876049 | 0.94 | TSHR (0.48) | TSHRMAPK1RECQLP2RX7KMT2A | |
| SCHEMBL8875758 | 0.87 | TSHR (0.41) | TSHRMAPK1RECQLP2RX7KMT2A | |
| SCHEMBL8877223 | 0.84 | TSHR (0.46) | TSHRMAPK1RECQLP2RX7KMT2A | |
| SCHEMBL8876722 | 0.83 | TSHR (0.44) | TSHRMAPK1RECQLP2RX7KMT2A | |
| SCHEMBL8313154 | 0.83 | KMT2A (0.41) | TSHRP2RX7KMT2AERCC1ERCC4 | |
| SCHEMBL8876826 | 0.83 | TSHR (0.46) | TSHRMAPK1RECQLP2RX7KMT2A | |
| SCHEMBL8877202 | 0.82 | P2RX7 (0.43) | TSHRMAPK1RECQLP2RX7KMT2A | |
| SCHEMBL8875634 | 0.81 | KMT2A (0.42) | TSHRMAPK1RECQLKMT2AERCC1 | |
| SCHEMBL8876904 | 0.81 | KMT2A (0.54) | TSHRP2RX7KMT2AMEN1ALDH1A1 | |
| SCHEMBL8875647 | 0.80 | TSHR (0.45) | TSHRMAPK1RECQLP2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4338390-A | — | — | None | — | — | JP | disclosed |
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| JP-H04338390-A | BICYCLIC 3-ARYL-PYRROLIDIN-2,4-DIONE DERIVATIVE | BAYER AG | 1992-11-25 | — | — | JP | disclosed |