Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492695 | 0.90 | HAO1 (0.60) | TTKLTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL12479877 | 0.88 | MAOB (0.53) | TTKLTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL627903 | 0.84 | TTK (0.59) | TTKLTA4HPLA2G2APLAUPLAT | |
| SCHEMBL17782603 | 0.83 | TTK (0.49) | TTKLTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL492124 | 0.83 | GABRA1 (0.63) | TTKMEN1HSP90AA1KMT2AGSK3B | |
| SCHEMBL6600100 | 0.82 | GABRA1 (0.61) | TTKLTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL12480296 | 0.82 | GSK3B (0.49) | TTKLTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL5988579 | 0.80 | TTK (0.53) | TTKLTA4HPLA2G2AMEN1HSP90AA1 | |
| SCHEMBL492399 | 0.80 | ALDH1A1 (0.56) | TTKMEN1KMT2AGSK3BKDM4E | |
| Tert-Butyl Formate SCHEMBL28002279 | 0.79 | GSK3B (0.46) | TTKLTA4HPLA2G2AMEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |