Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880495 | 0.92 | HTR4 (0.40) | KDM4EHPGDALDH1A1HSD17B10HTR4 | |
| SCHEMBL8732186 | 0.91 | KDM4E (0.45) | KDM4EHPGDALDH1A1HSD17B10HTR4 | |
| SCHEMBL8877789 | 0.87 | KDM4E (0.47) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL8736445 | 0.83 | KDM4E (0.50) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL8876328 | 0.78 | KDM4E (0.53) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL8970482 | 0.77 | MEN1 (0.35) | KDM4EHSD17B10 | |
| SCHEMBL8735573 | 0.76 | KDM4E (0.36) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL8879095 | 0.74 | KDM4E (0.48) | KDM4EHPGDALDH1A1HSD17B10TOP1 | |
| SCHEMBL8735859 | 0.73 | KDM4E (0.33) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL8878712 | 0.72 | KCNH2 (0.55) | KDM4EHPGDALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | claimed |
| US-5688791-A | COMPOUNDS FOR TREATMENNT OF VIRAL DISEASES SUCH AS AIDS | UBE INDUSTRIES, LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |