Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877789 | 0.79 | KDM4E (0.47) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL8877142 | 0.77 | KDM4E (0.39) | KDM4EHSD17B10 | |
| SCHEMBL8733968 | 0.74 | IKBKB (0.34) | — | |
| SCHEMBL8736445 | 0.73 | KDM4E (0.50) | MEN1KMT2AKDM4ETSHRHSD17B10 | |
| SCHEMBL8879095 | 0.70 | KDM4E (0.48) | KDM4ERECQLHSD17B10 | |
| SCHEMBL537485 | 0.70 | KCNH2 (0.37) | KDM4EHSD17B10 | |
| SCHEMBL8880495 | 0.70 | HTR4 (0.40) | MEN1KMT2AKDM4EGAAHSD17B10 | |
| SCHEMBL8735573 | 0.70 | KDM4E (0.36) | KDM4ERECQLHSD17B10 | |
| SCHEMBL8878712 | 0.70 | KCNH2 (0.55) | MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL8732186 | 0.69 | KDM4E (0.45) | MEN1KMT2AKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | claimed |
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |