Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 3/20 | 0.56 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520785 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KMT2ALMNAMEN1GAA | |
| SCHEMBL743694 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMEN1KDM4E | |
| SCHEMBL8877723 | 0.84 | CYP2D6 (0.57) | ALDH1A1KMT2ASMN1; SMN2POLBMEN1 | |
| SCHEMBL2702763 | 0.83 | CYP2D6 (0.64) | ALDH1A1KMT2ASMN1; SMN2POLBMEN1 | |
| SCHEMBL16864106 | 0.82 | LMNA (0.72) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL12946592 | 0.82 | SMN1; SMN2 (0.71) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL745232 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL6521662 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1GAA | |
| SCHEMBL16111988 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL969926 | 0.81 | LMNA (0.67) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618830-A | TREATING INFLUENZA, PREVENTING INFECTION BY INFLUENZA VIRUS | MERCK & CO., INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-5475109-A | Useful in prevention or treatment of infection by influenza virus | MERCK & CO., INC. (US) | 1995-12-12 | — | — | US | disclosed |