Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877568 | 0.86 | HMGCR (0.58) | GCGRHMGCR | |
| SCHEMBL8877852 | 0.85 | GCGR (0.49) | GCGRHMGCR | |
| SCHEMBL8878690 | 0.85 | GCGR (0.46) | GCGRHMGCR | |
| SCHEMBL6963687 | 0.84 | GCGR (0.62) | GCGRHMGCR | |
| SCHEMBL8878154 | 0.81 | DHODH (0.44) | GCGRHMGCR | |
| SCHEMBL8876796 | 0.79 | HMGCR (0.46) | GCGRHMGCR | |
| SCHEMBL8878764 | 0.79 | HMGCR (0.44) | GCGRHMGCR | |
| SCHEMBL2663566 | 0.79 | GCGR (0.58) | GCGR | |
| SCHEMBL8878033 | 0.79 | GCGR (0.55) | GCGR | |
| SCHEMBL8877555 | 0.78 | HMGCR (0.48) | GCGRHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691322-A | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5686433-A | CHOLESTEROL BIOSYNTHESIS INHIBITION | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5506219-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1996-04-09 | — | — | US | disclosed |