Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | BCKDK | O14874 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121489 | 0.86 | MAPT (0.50) | MCL1RXFP1BCKDKKDM4EMAPT | |
| SCHEMBL2723054 | 0.86 | BCKDK (0.75) | MCL1RXFP1BCKDKNPC1RAB9A | |
| SCHEMBL1255148 | 0.83 | BCKDK (0.58) | MCL1RXFP1BCKDKNPC1RAB9A | |
| SCHEMBL1254412 | 0.83 | MCL1 (0.51) | MCL1RXFP1BCKDKNPC1RAB9A | |
| SCHEMBL11798884 | 0.82 | ABCB11 (0.47) | MCL1RXFP1BCKDKKDM4EMAPT | |
| SCHEMBL1447569 | 0.81 | PRNP (0.60) | RXFP1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL12553241 | 0.80 | MCL1 (0.41) | MCL1RXFP1BCKDKNPC1RAB9A | |
| SCHEMBL3067147 | 0.80 | MCL1 (0.41) | MCL1RXFP1BCKDKNPC1RAB9A | |
| SCHEMBL12581557 | 0.80 | MCL1 (0.41) | MCL1RXFP1BCKDKNPC1RAB9A | |
| SCHEMBL144003 | 0.79 | MCL1 (0.42) | MCL1RXFP1BCKDKNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731800-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLOROBENZO [b]THIOPHENE-2-CARBONYL CHLORIDES | WARNER-LAMBERT COMPANY (US) | 1996-09-18 | — | — | EP | claimed |
| US-5426191-A | Treating substituted cinnamic acids with 4-N,N*-disubstituted aminopyridines, then with thionyl chloride | WARNER-LAMBERT COMPANY (US) | 1995-06-20 | — | — | US | claimed |
| WO-1995015323-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLOROBENZO[b]THIOPHENE-2-CARBONYL CHLORIDES | WARNER-LAMBERT COMPANY (US) | 1995-06-08 | — | — | WO | claimed |
| US-5608074-A | Process for the synthesis of 5-amino tetrazole derivatives | WARNER-LAMBERT COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0731800-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLOROBENZO [b]THIOPHENE-2-CARBONYL CHLORIDES | WARNER-LAMBERT COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5426191-A | Treating substituted cinnamic acids with 4-N,N*-disubstituted aminopyridines, then with thionyl chloride | WARNER-LAMBERT COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| WO-1995015323-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 3-CHLOROBENZO[b]THIOPHENE-2-CARBONYL CHLORIDES | WARNER-LAMBERT COMPANY (US) | 1995-06-08 | — | — | WO | disclosed |