Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 5/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA6 | P23280 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877844 | 1.00 | CA12 (0.53) | CA12CA7CA9CA14CA1 | |
| SCHEMBL8881390 | 0.88 | MET (0.49) | CA12CA7CA9CA14CA1 | |
| SCHEMBL8881396 | 0.88 | MET (0.49) | CA12CA7CA9CA14CA1 | |
| SCHEMBL14504338 | 0.80 | MEN1 (0.41) | CA12CA7CA9CA14CA1 | |
| SCHEMBL18503040 | 0.79 | FDPS (0.67) | CA12CA7CA9CA14CA1 | |
| SCHEMBL11442415 | 0.79 | CA12 (0.69) | CA12CA7CA9CA14CA1 | |
| SCHEMBL11442416 | 0.79 | CA12 (0.69) | CA12CA7CA9CA14CA1 | |
| SCHEMBL28223264 | 0.79 | CA12 (0.69) | CA12CA7CA9CA14CA1 | |
| SCHEMBL23066425 | 0.78 | ESR1 (0.47) | CA12CA7CA9CA14CA1 | |
| SCHEMBL20358018 | 0.77 | CA12 (0.67) | CA12CA7CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624948-A | TREATMENT OF BRONCHIAL ASTHMA | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0699668-A1 | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 1996-03-06 | — | — | EP | disclosed |