Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877039 | 0.86 | MYC (0.58) | MYCSMN1; SMN2TSHRCASP1SERPINE1 | |
| SCHEMBL7815535 | 0.80 | MYC (0.57) | MYCSERPINE1ALDH1A1HPGDMAPK1 | |
| SCHEMBL28946278 | 0.79 | ALDH1A1 (0.49) | TSHRALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL7820971 | 0.77 | DNMT3A (0.55) | MYCSMN1; SMN2TSHRCASP1ALDH1A1 | |
| SCHEMBL8877051 | 0.75 | ALDH1A1 (0.45) | MYCSERPINE1ALDH1A1TP53CA1 | |
| SCHEMBL29671348 | 0.75 | ALDH1A1 (0.61) | MYCSMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL228778 | 0.75 | ALDH1A1 (0.61) | MYCSMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL28946277 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1KDM4EPOLB | |
| SCHEMBL1586769 | 0.74 | MYC (0.57) | MYCSMN1; SMN2TSHRCASP1ALDH1A1 | |
| SCHEMBL14680352 | 0.74 | MYC (1.00) | MYCSMN1; SMN2TSHRCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-09-29 | — | — | US | disclosed |
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-09-29 | — | — | US | disclosed |
| EP-3442958-B1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| EP-3442958-B1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-20190112291-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
| US-20190112291-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
| WO-2017178340-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |
| US-5627203-A | INHIBITORS OF SEROTONIN REUPTAKE, HIGH AFFINITY FOR 5HT RECEPTORS, ANXIOLYTIC, ANTIDEPRESSANT | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787432-B2 | N-[(pyridyloxy)propanyl]benzamides | HCRTR1, HCRTR2, CNR1 | MYC 3984/4885SMN1; SMN2 1231/4885TSHR 195/4885 |
| US-20190112291-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | HCRTR1, HCRTR2, CNR1 | MYC 3881/4885SMN1; SMN2 1344/4885TSHR 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.