Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A15 | Q9H2J7 | 11/20 | 0.72 |
| ▸ | FNTA | P49354 | 8/20 | 0.72 |
| ▸ | FNTB | P49356 | 8/20 | 0.72 |
| ▸ | HRH1 | P35367 | 5/20 | 0.72 |
| ▸ | PTAFR | P25105 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | GMNN | O75496 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879009 | 0.90 | SLC6A15 (0.74) | SLC6A15FNTAFNTBHRH1PTAFR | |
| SCHEMBL8880256 | 0.89 | FNTA (0.78) | SLC6A15FNTAFNTBHRH1PTAFR | |
| SCHEMBL31350768 | 0.89 | FNTA (0.78) | SLC6A15FNTAFNTBHRH1PTAFR | |
| SCHEMBL8879451 | 0.87 | FNTA (0.85) | SLC6A15FNTAFNTBHRH1PTAFR | |
| SCHEMBL8879257 | 0.85 | FNTA (0.89) | SLC6A15FNTAFNTBHRH1PTAFR | |
| SCHEMBL3367280 | 0.85 | SLC6A15 (0.82) | SLC6A15FNTAFNTBHRH1PTAFR | |
| SCHEMBL8878143 | 0.85 | FNTA (0.78) | SLC6A15FNTAFNTBHRH1PTAFR | |
| Sch-37370 SCHEMBL3071641 | 0.84 | PTAFR (1.00) | SLC6A15FNTAFNTBHRH1PTAFR | |
| Sch-37370 SCHEMBL29626524 | 0.84 | PTAFR (1.00) | SLC6A15FNTAFNTBHRH1PTAFR | |
| Sch-37370 SCHEMBL29754039 | 0.84 | PTAFR (1.00) | SLC6A15FNTAFNTBHRH1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |