Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 17/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 17/20 | 0.50 |
| ▸ | PRKDC | P78527 | 17/20 | 0.50 |
| ▸ | ABL1 | P00519 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 4/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | HCK | P08631 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887847 | 0.81 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL887825 | 0.80 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8323143 | 0.79 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL2908004 | 0.77 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL887796 | 0.75 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL14742662 | 0.73 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL3420175 | 0.71 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL3423942 | 0.69 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL3422985 | 0.69 | ABL1 (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8325669 | 0.67 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | claimed |
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | claimed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | claimed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | claimed |
| US-7723038-B2 | Amplification methods | ELITECH HOLDING B.V. (NL) | 2010-05-25 | — | — | US | claimed |
| US-7715989-B2 | Systems and methods for predicting oligonucleotide melting temperature (TmS) | ELITECH HOLDING B.V. (NL) | 2010-05-11 | — | — | US | claimed |
| US-7553643-B2 | Method for amplifying target nucleic acid sequences using a primer comprising an AP endonuclease-cleavable linker | EPOCH BIOSCIENCES, INC. (US) | 2009-06-30 | — | — | US | claimed |
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2008-11-27 | — | — | US | claimed |
| US-20080248474-A1 | AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC (US) | 2008-10-09 | — | — | US | claimed |
| US-7381818-B2 | Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof | EPOCH BIOSCIENCES, INC. (US) | 2008-06-03 | — | — | US | claimed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | claimed |
| EP-1687609-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | Epoch Biosciences, Inc. (US) | 2006-08-09 | — | — | EP | claimed |
| EP-1468112-A4 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | EPOCH BIOSCIENCES INC (US) | 2005-11-23 | — | — | EP | claimed |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | EPOCH BIOSCIENCES, INC (US) | 2005-09-29 | — | — | US | claimed |
| WO-2005043127-A2 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| EP-1468112-A2 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | Epoch Biosciences, Inc. (US) | 2004-10-20 | — | — | EP | claimed |
| US-20030175728-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2003-09-18 | — | — | US | claimed |
| WO-2003062445-A2 | REAL-TIME LINEAR DETECTION PROBES: SENSITIVE 5'-MINOR GROOVE BINDER-CONTAINING PROBES FOR PCR ANALYSIS | EPOCH BIOSCIENCES, INC. (US) | 2003-07-31 | — | — | WO | claimed |
| US-12571025-B2 | Isolation and detection of DNA from plasma | EXACT SCIENCES CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| WO-2001064958-A2 | MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION | EPOCH BIOSCIENECS, INC. (US) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | SSBP1, DDB1, DNA2 | PIK3CD 4646/4885PIK3CA 4403/4885PIK3CB 3883/4885 |
| US-20030175728-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | RNGTT, DCLRE1B, CNBP | PIK3CD 4285/4885PIK3CA 3942/4885PIK3CB 2889/4885 |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | SSBP1, DDB1, DNA2 | PIK3CD 4646/4885PIK3CA 4403/4885PIK3CB 3883/4885 |
| US-12571025-B2 | Isolation and detection of DNA from plasma | DNMT3A, DNMT1, DNMT3B | PIK3CD 375/4885PIK3CA 845/4885PIK3CB 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.