Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809642 | 0.85 | MAPT (0.68) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1712953 | 0.81 | MAPT (0.58) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1720494 | 0.81 | MAPT (0.72) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5885563 | 0.80 | MAPT (0.70) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL900124 | 0.80 | MAPT (0.70) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5605709 | 0.79 | ALDH1A1 (0.66) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7400389 | 0.79 | ALDH1A1 (0.66) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6983298 | 0.78 | MAPT (0.68) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13130067 | 0.78 | MAPT (0.68) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12297020 | 0.78 | ALDH1A1 (0.69) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |