SCHEMBL8878286

SCHEMBL8878286

Cc1c(C)c2c(c(Cl)c1C=O)OC(C)(C)C2

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8878076 0.85 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8876889 0.85 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8878018 0.81 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8877911 0.80 ALDH1A1 (0.31) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8877915 0.80 ALDH1A1 (0.31) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8069880 0.73 PTPRF (0.33)
SCHEMBL8747110 0.70 ALDH1A1 (0.33) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL7875364 0.69 HPGD (0.38) CYP1A2CYP3A4
SCHEMBL14141359 0.69 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2
SCHEMBL8878550 0.68 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631208-A Herbicidal cyclohexane-1,3-dione derivatives and their preparation process KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-05-20 US disclosed
WO-1994003443-A1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1994-02-17 WO disclosed