SCHEMBL8069880

SCHEMBL8069880

Cc1c(C)c2c(c(Cl)c1C=O)CC(C)(C)C2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPRF P10586 2/20 0.33
PTPRC P08575 1/20 0.33
PTPRM P28827 1/20 0.33
PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067811 0.87 PTPRF (0.34) PTPRFPTPRCPTPRMPTPN11
SCHEMBL8070209 0.84 PTPRF (0.36) PTPRFPTPRCPTPRMPTPN11
SCHEMBL8058764 0.83 KDM4E (0.35)
SCHEMBL8878286 0.73 ALDH1A1 (0.34)
SCHEMBL8069794 0.70 KDM4E (0.36)
SCHEMBL8072667 0.67 KDM4E (0.39)
SCHEMBL29142717 0.65 MEN1 (0.36)
SCHEMBL8067821 0.65 LMNA (0.30)
SCHEMBL8067818 0.65 LMNA (0.30)
SCHEMBL8074398 0.64 TP53 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6096930-A PREPARATION OF 2-METHYLINDANECARBOXYALDEHYDES BY REACTING A MALONYL HALIDE WITH A BENZENE DERIVATIVE, REDUCTION OF THE FORMED INDANEDIONE, REACTION WITH DICHLOROMETHYL METHYL ETHER KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-08-01 US disclosed
WO-1996006071-A1 NOVEL HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-02-29 WO disclosed