Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486647 | 0.84 | KDM4E (0.51) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL9016431 | 0.84 | KDM4E (0.43) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL18380643 | 0.81 | KDM4E (0.61) | KDM4EMAPTALDH1A1ATMLMNA | |
| SCHEMBL11085738 | 0.80 | KDM4E (0.42) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL4159068 | 0.78 | KDM4E (0.54) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL11080851 | 0.77 | KDM4E (0.42) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL9090229 | 0.77 | KDM4E (0.37) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL2089146 | 0.76 | KDM4E (0.53) | KDM4EIL2MAPTALDH1A1ATM | |
| SCHEMBL19287365 | 0.76 | KDM4E (0.43) | KDM4EESR1IL2MAPTMEN1 | |
| SCHEMBL7490435 | 0.75 | KDM4E (0.47) | KDM4EIL2MAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608068-A | Process for the preparation of imidazopyridine derivatives and intermediates | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |