Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080851 | 0.91 | KDM4E (0.42) | KDM4EHPGDATMHTTALDH1A1 | |
| SCHEMBL7831700 | 0.90 | KDM4E (0.45) | KDM4EHPGDATMHTTALDH1A1 | |
| SCHEMBL11486647 | 0.84 | KDM4E (0.51) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL8878641 | 0.84 | KDM4E (0.43) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL18380643 | 0.81 | KDM4E (0.61) | KDM4EHPGDATMHTTALDH1A1 | |
| SCHEMBL11491135 | 0.80 | KDM4E (0.47) | KDM4EHPGDATMHTTALDH1A1 | |
| SCHEMBL4159068 | 0.78 | KDM4E (0.54) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL11085738 | 0.77 | KDM4E (0.42) | KDM4EHPGDATMHTTALDH1A1 | |
| SCHEMBL498998 | 0.77 | KDM4E (0.44) | KDM4EHPGDATMHTTALDH1A1 | |
| SCHEMBL9090229 | 0.77 | KDM4E (0.37) | KDM4EHPGDATMHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |