Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558525 | 0.89 | ALOX15 (0.46) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22635 | 0.86 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29963833 | 0.86 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL31229322 | 0.86 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1355526 | 0.86 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29399939 | 0.86 | ALOX15 (0.47) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28528741 | 0.85 | ALOX15 (0.46) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5550242 | 0.85 | ALOX15 (0.46) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| Water SCHEMBL28274879 | 0.85 | ALOX15 (0.46) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8878983 | 0.82 | ALDH1A1 (0.57) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594140-A | Imidazo[1,5-A]quinolines for treatment of anxiety and sleep disorders | THE UPJOHN COMPANY (US) | 1997-01-14 | — | — | US | disclosed |