SCHEMBL887920

SCHEMBL887920

CC=CCNCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
DPP7 Q9UHL4 1/20 0.50
RAB9A P51151 1/20 0.49
ADH1B P00325 1/20 0.47
ADH1C P00326 1/20 0.47
ADH1A P07327 1/20 0.47
ADH7 P40394 1/20 0.47
MAOA P21397 1/20 0.47
TK1 P04183 1/20 0.46
MAPT P10636 2/20 0.45
CHRM2 P08172 1/20 0.45
GAA P10253 1/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP3A4 P08684 1/20 0.45
HDAC3 O15379 1/20 0.44
SIGMAR1 Q99720 1/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2720624 1.00 MEN1 (0.52) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL14602897 1.00 MEN1 (0.52) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL15607673 0.89 MEN1 (0.64) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL28668988 0.88 RAB9A (0.48) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL12658313 0.85 MEN1 (0.45) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL16869633 0.83 MEN1 (0.52) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL6616250 0.81 MAOB (0.65) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL8781417 0.81 MEN1 (0.54) MEN1KMT2ATDP1DPP7RAB9A
SCHEMBL20921313 0.80 SIGMAR1 (0.57) MEN1KMT2ARAB9AMAOAMAPT
SCHEMBL21574007 0.80 MEN1 (0.48) MEN1KMT2ATDP1DPP7RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884405-B Lubricating oil composition 出光兴产株式会社 2023-01-17 CN claimed
CN-107429188-B Lubricating oil composition 出光兴产株式会社 2020-12-18 CN claimed
CN-106414687-B Lubricating oil composition for internal combustion engine 出光兴产株式会社 2020-08-25 CN claimed
CN-102933578-B Cyano-quinoline derivatives 天津和美生物技术有限公司 2016-09-07 CN claimed
CN-115485049-B Defoaming agent and lubricating oil composition 引能仕株式会社 2024-04-26 CN disclosed
US-11965142-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2024-04-23 US disclosed
EP-3950905-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2024-01-17 EP disclosed
US-11718810-B2 Lubricating oil composition and method for defoaming lubricating oil, and defoaming agent composition ENEOS CORPORATION (JP) 2023-08-08 US disclosed
US-20230159848-A1 DEFOAMING AGENT AND LUBRICATING OIL COMPOSITION ENEOS CORPORATION (JP) 2023-05-25 US disclosed
CN-113543866-B Lubricating oil composition, defoaming method for lubricating oil, and defoaming agent composition 引能仕株式会社 2023-01-31 CN disclosed
CN-108884405-B Lubricating oil composition 出光兴产株式会社 2023-01-17 CN disclosed
EP-4112150-A1 ANTIFOAMING AGENT, AND LUBRICATING OIL COMPOSITION ENEOS Corporation (JP) 2023-01-04 EP disclosed
US-5712343-A Preparation of organopolysiloxane microemulsions WACKER-CHEMIE GMBH (DE) 1998-01-27 US disclosed
US-5630474-A ENHANCED OIL RECOVERY USING AQUEOUS EMULSION CONTAINING POLYSILOXANE AND SURFACTANT WACKER-CHEMIE GMBH (DE) 1997-05-20 US disclosed
US-5523365-A Graft copolymers of organopolysiloxanes as free radical macroinitiators WACKER-CHEMIE GMBH (DE) 1996-06-04 US disclosed
EP-0413455-B1 Azabicyclo quinolone carboxylic acids PFIZER (US) 1995-06-21 EP disclosed
US-5391763-A 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids PFIZER INC. (US) 1995-02-21 US disclosed
US-5266569-A Azatricyclo carboxylic acids useful as anti-bacterial agents PFIZER INC. (US) 1993-11-30 US disclosed
US-5229396-A Anti-bacterial azabicyclo quinolone carboxylic acids PFIZER INC. (US) 1993-07-20 US disclosed
US-5164402-A Bactericides PFIZER INC (US) 1992-11-17 US disclosed