Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 10/20 | 0.74 |
| ▸ | FNTA | P49354 | 7/20 | 0.69 |
| ▸ | FNTB | P49356 | 7/20 | 0.69 |
| ▸ | HRH1 | P35367 | 3/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | SLC6A15 | Q9H2J7 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879257 | 0.88 | FNTA (0.89) | PTAFRFNTAFNTBHRH1CHRM2 | |
| SCHEMBL9592515 | 0.87 | FNTA (0.71) | PTAFRFNTAFNTBHRH1SLC6A15 | |
| SCHEMBL9590605 | 0.86 | FNTA (0.67) | PTAFRFNTAFNTBHRH1SLC6A15 | |
| SCHEMBL9591037 | 0.86 | FNTA (0.66) | PTAFRFNTAFNTBHRH1SLC6A15 | |
| SCHEMBL8877892 | 0.85 | PTAFR (1.00) | PTAFRFNTAFNTBHRH1CHRM2 | |
| SCHEMBL9593377 | 0.85 | FNTA (0.65) | PTAFRFNTAFNTBHRH1SLC6A15 | |
| SCHEMBL8876671 | 0.83 | PTAFR (0.64) | PTAFRFNTAFNTBHRH1CHRM2 | |
| SCHEMBL9075282 | 0.83 | HRH1 (0.73) | PTAFRFNTAFNTBHRH1CHRM2 | |
| SCHEMBL30056292 | 0.82 | HRH1 (0.80) | PTAFRFNTAFNTBHRH1CHRM2 | |
| SCHEMBL9073792 | 0.82 | HRH1 (0.80) | PTAFRFNTAFNTBHRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0685476-A1 | Benzo(5,6)cycloheptapyridines, compositions and methods of use | SCHERING CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5438062-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0270818-B1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORP (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0330673-A1 | BENZO 5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |
| US-4826853-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0270818-A1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988003138-A1 | BENZO[5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |