Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.79 |
| ▸ | FNTA | P49354 | 3/20 | 0.75 |
| ▸ | FNTB | P49356 | 3/20 | 0.75 |
| ▸ | PTAFR | P25105 | 5/20 | 0.72 |
| ▸ | SLC6A15 | Q9H2J7 | 5/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877712 | 0.90 | PTAFR (0.72) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL8879730 | 0.89 | HRH1 (0.79) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL6180028 | 0.85 | FNTA (0.75) | HRH1FNTAFNTBSLC6A15 | |
| Sch-37370 SCHEMBL29754039 | 0.84 | PTAFR (1.00) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| Sch-37370 SCHEMBL29626524 | 0.84 | PTAFR (1.00) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| Sch-37370 SCHEMBL3071641 | 0.84 | PTAFR (1.00) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL6179997 | 0.83 | FNTA (0.76) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL6177625 | 0.82 | HRH1 (1.00) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL9373907 | 0.80 | PTAFR (0.74) | HRH1FNTAFNTBPTAFRSLC6A15 | |
| SCHEMBL8879119 | 0.80 | PTAFR (0.74) | HRH1FNTAFNTBPTAFRSLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | claimed |
| US-5665726-A | ANTIALLERGIC, ANTIINFLAMMATORY AGENTS | SCHERING CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0685476-A1 | Benzo(5,6)cycloheptapyridines, compositions and methods of use | SCHERING CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5438062-A | Antiallergens, antiinflammatory agents | SCHERING CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0270818-B1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORP (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5089496-A | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies | SCHERING CORPORATION (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0330673-A1 | BENZO 5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0270818-A1 | Benzo(5,6)cycloheptapyridines, compositions and method of use | SCHERING CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988003138-A1 | BENZO[5,6]CYCLOHEPTAPYRIDINES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |