Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 12/20 | 0.74 |
| ▸ | SLC6A15 | Q9H2J7 | 6/20 | 0.74 |
| ▸ | FNTA | P49354 | 5/20 | 0.74 |
| ▸ | FNTB | P49356 | 5/20 | 0.74 |
| ▸ | HRH1 | P35367 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992437 | 0.88 | SLC6A15 (0.77) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| SCHEMBL9387368 | 0.87 | FNTA (0.82) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| SCHEMBL9208366 | 0.87 | FNTA (0.65) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| Sch-37370 SCHEMBL29754039 | 0.85 | PTAFR (1.00) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| Sch-37370 SCHEMBL3071641 | 0.85 | PTAFR (1.00) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| Sch-37370 SCHEMBL29626524 | 0.85 | PTAFR (1.00) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| SCHEMBL8879730 | 0.84 | HRH1 (0.79) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| SCHEMBL8880503 | 0.83 | PTAFR (1.00) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| SCHEMBL6998698 | 0.82 | FNTA (0.61) | PTAFRSLC6A15FNTAFNTBHRH1 | |
| SCHEMBL6998702 | 0.82 | FNTA (0.61) | PTAFRSLC6A15FNTAFNTBHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341860-B1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORP (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0411048-A1 | NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1991-02-06 | — | — | EP | claimed |
| EP-0341860-A1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORPORATION (US) | 1989-11-15 | — | — | EP | claimed |
| WO-1989010369-A1 | NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | claimed |
| EP-0341860-B1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORP (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5104876-A | Antiallergens, antiinflammatory agent | SCHERING CORPORATION | 1992-04-14 | — | — | US | disclosed |
| EP-0411048-A1 | NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1991-02-06 | — | — | EP | disclosed |
| EP-0341860-A1 | Benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use | SCHERING CORPORATION (US) | 1989-11-15 | — | — | EP | disclosed |
| WO-1989010369-A1 | NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |