SCHEMBL8879680

SCHEMBL8879680

C#CCCOc1cc(N2C(=O)CC(C(F)(F)F)CC2=O)c(F)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPOX P50336 13/20 0.38
SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8879696 0.89 PPOX (0.40) PPOX
SCHEMBL8881338 0.81 PPOX (0.52) PPOX
SCHEMBL9219715 0.80 PPOX (0.38) PPOX
SCHEMBL8878129 0.80 PPOX (0.42) PPOXSCN9A
SCHEMBL8879250 0.77 PPOX (0.36) PPOX
SCHEMBL10448351 0.76 PPOX (0.43) PPOX
SCHEMBL9562807 0.76 PPOX (0.40) PPOXSCN9A
SCHEMBL8877808 0.75 PPOX (0.40) PPOX
SCHEMBL8878859 0.75 MAPT (0.36)
SCHEMBL8879045 0.74 PPOX (0.35) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631209-A ALGICIDES ROHM AND HAAS COMPANY (US) 1997-05-20 US disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed