SCHEMBL8879696

SCHEMBL8879696

C#CCOc1cc(N2C(=O)CC(C(F)(F)F)CC2=O)c(F)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPOX P50336 12/20 0.40
PGK1 P00558 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9219715 0.91 PPOX (0.38) PPOXPGK1
SCHEMBL8879680 0.89 PPOX (0.38) PPOX
SCHEMBL10448351 0.87 PPOX (0.43) PPOXPGK1
SCHEMBL8881338 0.83 PPOX (0.52) PPOX
SCHEMBL8878184 0.83 SCN9A (0.37) PPOXPGK1
SCHEMBL8878129 0.81 PPOX (0.42) PPOX
SCHEMBL8879250 0.79 PPOX (0.36) PPOX
SCHEMBL8686426 0.79 PPOX (0.39) PPOX
SCHEMBL9562807 0.77 PPOX (0.40) PPOX
SCHEMBL10690143 0.77 PPOX (0.43) PPOXPGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3163060-A None JP disclosed
US-5631209-A ALGICIDES ROHM AND HAAS COMPANY (US) 1997-05-20 US disclosed
US-5502027-A ALGICIDES ROHM AND HAAS COMPANY (US) 1996-03-26 US disclosed
EP-0415642-B1 Glutarimides ROHM & HAAS (US) 1995-12-06 EP disclosed
US-5393735-A N-(halo-oxy-)phenyl substituted cyclic imides ROHM AND HAAS COMPANY (US) 1995-02-28 US disclosed
JP-H03163060-A HERBICIDAL COMPOUNDS ROHM & HAAS CO 1991-07-15 JP disclosed
EP-0415642-A1 Glutarimides ROHM AND HAAS COMPANY (US) 1991-03-06 EP disclosed