Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 2/20 | 0.30 |
| ▸ | TACR3 | P29371 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879769 | 1.00 | TACR2 (0.30) | TACR2TACR3CHRM2HTR1ADRD3 | |
| SCHEMBL8882083 | 0.89 | SLC5A7 (0.34) | — | |
| SCHEMBL8882085 | 0.89 | SLC5A7 (0.34) | — | |
| SCHEMBL8880178 | 0.89 | LMNA (0.35) | TACR2TACR3CHRM2HTR1ADRD3 | |
| SCHEMBL10590242 | 0.84 | TACR2 (0.31) | TACR2TACR3TACR1 | |
| SCHEMBL10766966 | 0.84 | DRD2 (0.37) | DRD3 | |
| SCHEMBL8880380 | 0.83 | — | — | |
| SCHEMBL9826701 | 0.83 | DRD2 (0.32) | TACR2TACR3DRD3TACR1 | |
| SCHEMBL8880246 | 0.83 | ALOX5AP (0.36) | CHRM2HTR1ADRD3HTR2B | |
| SCHEMBL8880923 | 0.83 | MEN1 (0.40) | CHRM2HTR1ADRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604225-A | DIETETICS; OBESITY | DR. KARL THOMAE GMBH (DE) | 1997-02-18 | — | — | US | disclosed |
| US-5219852-A | Hypoglycemic agents, treatment of diabetes and obesity | DR. KARL THOMAE GMBH (DE) | 1993-06-15 | — | — | US | disclosed |
| US-4886814-A | LOWER BLOOD SUGAR | DR. KARL THOMAS GMBH (DE) | 1989-12-12 | — | — | US | disclosed |