Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CBR1 | P16152 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383766 | 0.81 | GAA (0.54) | LMNAMAPTHSP90AA1HPGDGAA | |
| SCHEMBL932130 | 0.77 | HTR2A (0.42) | ARSLC6A4HTR2AKCNH2GAA | |
| SCHEMBL24636846 | 0.77 | TTR (0.42) | AKR1B1SLC6A2SLC6A3TTRLMNA | |
| SCHEMBL12129123 | 0.75 | KDM4E (0.51) | LMNAMAPTGAATSHRALDH1A1 | |
| SCHEMBL23183252 | 0.75 | CSNK2A1 (0.47) | LMNAMAPTNR1I2HPGDGAA | |
| SCHEMBL30805782 | 0.75 | KDM4E (0.51) | LMNAMAPTGAATSHRALDH1A1 | |
| SCHEMBL172591 | 0.75 | CD44 (0.45) | LMNAHPGDTBXA2RCD44TSHR | |
| SCHEMBL921091 | 0.73 | AR (0.51) | ARSLC6A4HTR2AKCNH2SLC6A3 | |
| SCHEMBL921480 | 0.73 | ST14 (0.52) | SLC6A4HTR2AKCNH2F2F10 | |
| SCHEMBL28105594 | 0.73 | MPO (0.47) | SLC6A4HTR2AKCNH2AKR1B1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631208-A | Herbicidal cyclohexane-1,3-dione derivatives and their preparation process | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-05-20 | — | — | US | disclosed |
| WO-1994003443-A1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1994-02-17 | — | — | WO | disclosed |