SCHEMBL921480

SCHEMBL921480

Cc1cc(Cl)c(Oc2ccc(CN)cc2)cc1C

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.52
CSNK2A1 P68400 5/20 0.45
DPP4 P27487 1/20 0.42
HTR2A P28223 1/20 0.42
SLC6A4 P31645 1/20 0.42
KCNH2 Q12809 1/20 0.42
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
MAOB P27338 4/20 0.41
ROCK2 O75116 1/20 0.40
ROCK1 Q13464 1/20 0.40
FFAR1 O14842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12239016 0.85 ST14 (0.50) ST14CSNK2A1DPP4HTR2ASLC6A4
SCHEMBL12239009 0.82 ST14 (0.50) ST14CSNK2A1DPP4HTR2ASLC6A4
SCHEMBL12239022 0.79 ST14 (0.50) ST14CSNK2A1DPP4HTR2ASLC6A4
SCHEMBL2540071 0.79 ST14 (0.50) ST14CSNK2A1HTR2ASLC6A4KCNH2
SCHEMBL12239005 0.78 FFAR1 (0.60) ST14MAOBFFAR1
SCHEMBL15832064 0.78 ST14 (0.58) ST14CSNK2A1HTR2ASLC6A4KCNH2
SCHEMBL922082 0.78 ST14 (0.53) ST14SLC6A4MAOB
SCHEMBL10121244 0.78 ST14 (0.53) ST14DPP4HTR2ASLC6A4KCNH2
SCHEMBL920984 0.76 ST14 (0.66) ST14MAOB
SCHEMBL13904294 0.75 ST14 (0.50) ST14CSNK2A1DPP4MAOBROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885CSNK2A1 1850/4885DPP4 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.