SCHEMBL888020

SCHEMBL888020

O=Cc1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
CYP2A6 P11509 2/20 0.59
LMNA P02545 3/20 0.59
KDM4E B2RXH2 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
LTA4H P09960 3/20 0.57
TSHR P16473 1/20 0.57
PARP10 Q53GL7 1/20 0.57
PARP3 Q9Y6F1 1/20 0.57
TTR P02766 1/20 0.55
TLR4 O00206 1/20 0.53
TLR2 O60603 1/20 0.53
KMT2A Q03164 3/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.51
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
PPARG P37231 1/20 0.50
SRD5A2 P31213 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97639 1.00 ALDH1A1 (0.59) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL21023525 0.94 ALDH1A1 (0.53) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL5050902 0.90 PARP10 (0.65) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL1663469 0.90 PARP10 (0.65) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
Phenol SCHEMBL17941267 0.90 LTA4H (0.63) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL3079744 0.89 KMT2A (0.61) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL1747257 0.89 ALDH1A1 (0.55) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL4454575 0.88 ALDH1A1 (0.49) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
Phenol SCHEMBL17941265 0.87 LTA4H (0.59) ALDH1A1CYP2A6LMNAKDM4ESMN1; SMN2
SCHEMBL23259817 0.87 SRD5A2 (0.69) ALDH1A1LMNASMN1; SMN2PARP10PARP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9136036-B2 Injection moldable, thermoplastic composite materials Miller Waster Mills (US) 2015-09-15 US claimed
EP-2328978-A2 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills D/b/a Rtp Company (US) 2011-06-08 EP claimed
WO-2010002546-A2 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills d/b/a RTP Company (US) 2010-01-07 WO claimed
US-20100003438-A1 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS Miller Waste Mills d/b/a RTP Company 2010-01-07 US claimed
EP-0174030-B1 FLEXIBLE OPTICAL SOLAR REFLECTOR NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-07-18 EP claimed
EP-0174030-A2 Flexible optical solar reflector NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1986-03-12 EP claimed
US-11746188-B2 Poly(aryl-ether-ketone) (PAEK) powder suitable for multiple use in sintering methods ARKEMA FRANCE (FR) 2023-09-05 US disclosed
WO-2021219889-A1 INSULATED CONDUCTOR FOR USE IN A WINDING, WINDING DERIVED THEREFROM AND CORRESPONDING MANUFACTURING METHODS ARKEMA FRANCE (FR) 2021-11-04 WO disclosed
EP-2328978-B1 INJECTION MOLDABLE, THERMOPLASTIC COMPOSITE MATERIALS MILLER WASTE MILLS D B A RTP COMPANY (US) 2016-07-20 EP disclosed
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 US disclosed
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 US disclosed
US-9382496-B1 Lubricants with high thermal stability for heat-assisted magnetic recording WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2016-07-05 US disclosed
US-9136036-B2 Injection moldable, thermoplastic composite materials Miller Waster Mills (US) 2015-09-15 US disclosed
EP-0744405-A2 Cyclic peptide antifungal agents ELI LILLY AND COMPANY (US) 1996-11-27 EP disclosed
WO-1996031228-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-10-10 WO disclosed
EP-0736541-A1 Cyclic hexapeptide antifungal agents ELI LILLY AND COMPANY (US) 1996-10-09 EP disclosed
EP-0174030-B1 FLEXIBLE OPTICAL SOLAR REFLECTOR NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-07-18 EP disclosed
US-4666760-A POLYETHERIMIDE BLENDS, RADIATION RESISTANCE NIPPON TELEGRAPH & TELEPHONE CORPORATION (JP) 1987-05-19 US disclosed
EP-0174030-A2 Flexible optical solar reflector NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1986-03-12 EP disclosed
EP-0174030-A2 Flexible optical solar reflector NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1986-03-12 EP disclosed