Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8879608 | 0.98 | — | — | |
| SCHEMBL8879835 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL8879846 | 0.90 | — | — | |
| SCHEMBL20837330 | 0.68 | DGAT1 (0.43) | CTSCKCNH2CYP2C19ALDH1A1LMNA | |
| SCHEMBL3107018 | 0.66 | HDAC4 (0.42) | CTSCKCNH2CYP2C19ALDH1A1LMNA | |
| SCHEMBL4121086 | 0.66 | CYP3A4 (0.37) | CTSCKCNH2CYP2C19ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11798891 | 0.66 | HDAC4 (0.39) | CTSCKCNH2HDAC4 | |
| SCHEMBL1258017 | 0.65 | — | — | |
| SCHEMBL4133242 | 0.64 | CYP3A4 (0.40) | CTSCKCNH2CYP2C19ALDH1A1LMNA | |
| SCHEMBL28674194 | 0.64 | FAAH (0.50) | LMNAHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428053-A | Treats alzheimer's disease and other senile dementias | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | claimed |
| US-5605925-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-02-25 | — | — | US | disclosed |
| US-5580987-A | TREATING 1-PHTHALIMIDOPYRROLE WITH BASE TO YIELD 1-AMINOPYRROLE, REACTING WITH SUBSTITUTED AMINO ACID TO OBTAIN DESIRED COMPOUND | HOECHST MARION ROUSSEL, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5576446-A | GLYCINE PARTIAL AGONIST AND ENHANCEMENT OF LEARNING AND MEMORY, TREATMENT OF ALZHEIMER'S | HOECHST MARION ROUSSEL, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5428053-A | Treats alzheimer's disease and other senile dementias | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0582182-A1 | 1-Aminoacetamidopyrroles and 1-amino-2-(substituted) pyrroles and their use for the treatment of neurodegenerative dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-02-09 | — | — | EP | disclosed |
| US-5274116-A | 1-aminoacetamidopyrroles and 1-aminoacetamido-2-(substituted)pyrroles and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-12-28 | — | — | US | disclosed |