Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880596 | 0.84 | ALDH1A1 (0.44) | OPRD1OPRK1MAPTALDH1A1HTR2C | |
| SCHEMBL9880597 | 0.78 | ALDH1A1 (0.49) | OPRD1OPRK1ALDH1A1HTR2CP2RX4 | |
| SCHEMBL9880601 | 0.76 | ALDH1A1 (0.46) | OPRD1OPRK1ALDH1A1HTR2CP2RX4 | |
| SCHEMBL697760 | 0.75 | L3MBTL1 (0.38) | OPRD1OPRK1MAPTALDH1A1HTR2C | |
| SCHEMBL7514677 | 0.75 | JMJD6 (0.43) | OPRD1OPRK1ALDH1A1HTR2CJMJD6 | |
| SCHEMBL5648210 | 0.75 | SMN1; SMN2 (0.45) | OPRD1OPRK1MAPTALDH1A1P2RX4 | |
| SCHEMBL9880598 | 0.74 | ALDH1A1 (0.44) | OPRD1OPRK1ALDH1A1HTR2CP2RX4 | |
| SCHEMBL9880605 | 0.73 | P2RX4 (0.44) | MAPTALDH1A1P2RX4CYP2C19SMN1; SMN2 | |
| SCHEMBL9880609 | 0.73 | ESR1 (0.47) | OPRD1OPRK1ALDH1A1HTR2CP2RX4 | |
| SCHEMBL8905073 | 0.71 | AAK1 (0.53) | MAPTALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665753-A | TREATMENT OF MATRIX-DEGRADING METALLOPROTEINASE RELATED DISEASE STATES, I.E. ARTHRITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-09 | — | — | US | disclosed |