Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274510 | 0.84 | CRBN (0.53) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| Bromide SCHEMBL11199816 | 0.83 | CRBN (0.52) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| SCHEMBL11196268 | 0.77 | CRBN (0.52) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| SCHEMBL8807339 | 0.75 | SLC6A4 (0.52) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| Hydrochloric Acid SCHEMBL7286588 | 0.74 | SMYD3 (0.50) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| SCHEMBL7269908 | 0.74 | SLC6A4 (0.78) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| SCHEMBL31570658 | 0.73 | MAPT (0.43) | LMNAHTT | |
| SCHEMBL11194801 | 0.73 | SLC6A4 (0.64) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| SCHEMBL11197711 | 0.73 | PDE3B (0.53) | CRBNPDE3BPDE3ATBXAS1SLC6A4 | |
| SCHEMBL11200462 | 0.72 | SLC6A4 (0.49) | CRBNPDE3BPDE3ATBXAS1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |