Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887950 | 0.71 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL437249 | 0.67 | MEN1 (0.35) | — | |
| SCHEMBL7936022 | 0.65 | POLB (0.31) | — | |
| SCHEMBL16193295 | 0.61 | CYP19A1 (0.42) | CYP19A1GSTP1 | |
| SCHEMBL6253261 | 0.60 | CYP19A1 (0.35) | CYP19A1 | |
| SCHEMBL6246587 | 0.59 | GRIN2D (0.35) | CYP19A1 | |
| SCHEMBL3267931 | 0.57 | GSTP1 (0.45) | GSTP1 | |
| SCHEMBL18668717 | 0.57 | DPP4 (0.57) | — | |
| SCHEMBL3397061 | 0.57 | GSTP1 (0.30) | GSTP1 | |
| SCHEMBL11561765 | 0.57 | MMP9 (0.35) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010281-A1 | ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010281-A1 | ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010281-A1 | ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010281-A1 | ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS | TBK1, TBCD, TBKBP1 | CYP19A1 4879/4885GSTP1 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.