Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.67 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.67 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993277 | 0.84 | AVPR2 (0.85) | AVPR2AVPR1AAVPR1BLMNA | |
| SCHEMBL8796876 | 0.83 | AVPR2 (0.64) | AVPR2AVPR1AAVPR1BLMNA | |
| SCHEMBL8797804 | 0.80 | AVPR1A (1.00) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL8796707 | 0.80 | AVPR1A (0.74) | AVPR2AVPR1AAVPR1BLMNA | |
| SCHEMBL6989965 | 0.80 | AVPR1A (0.60) | AVPR2AVPR1AAVPR1BLMNACSF1R | |
| SCHEMBL8797156 | 0.80 | AVPR1A (0.73) | AVPR2AVPR1AAVPR1BLMNA | |
| SCHEMBL8796970 | 0.78 | AVPR1A (0.73) | AVPR2AVPR1AAVPR1BLMNA | |
| SCHEMBL6988420 | 0.78 | AVPR2 (0.55) | AVPR2AVPR1AAVPR1BCHRM4CHRM1 | |
| SCHEMBL8796809 | 0.77 | AVPR1A (0.79) | AVPR2AVPR1AAVPR1BLMNACHRM1 | |
| SCHEMBL8801105 | 0.77 | AVPR2 (0.72) | AVPR2AVPR1AAVPR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654297-A | CONGESTIVE HEART FAILURE, CARDIOVASCULAR DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1997-08-05 | — | — | US | disclosed |