Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880601 | 1.00 | CHRM1 (0.42) | CHRM1PGRTGM2CES1ALDH1A1 | |
| SCHEMBL8880752 | 0.84 | MAOB (0.41) | PGRTGM2CES1LRRK2IDO1 | |
| SCHEMBL8880758 | 0.84 | MAOB (0.41) | PGRTGM2CES1LRRK2IDO1 | |
| SCHEMBL8302328 | 0.82 | HPGD (0.34) | CHRM1TGM2CES1LRRK2IDO1 | |
| SCHEMBL8302332 | 0.82 | HPGD (0.34) | CHRM1TGM2CES1LRRK2IDO1 | |
| SCHEMBL8880687 | 0.82 | PGR (0.39) | CHRM1PGRTGM2CES1ALDH1A1 | |
| SCHEMBL27461474 | 0.78 | CHRM1 (0.32) | CHRM1 | |
| SCHEMBL27461472 | 0.78 | CHRM1 (0.32) | CHRM1 | |
| SCHEMBL8880980 | 0.74 | MDM2 (0.40) | PGRTGM2CES1LRRK2IDO1 | |
| SCHEMBL27373896 | 0.73 | TGM2 (0.32) | CHRM1TGM2CES1LRRK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579968-B1 | 4-Iminoquinolines, processes for their preparation and their use | HOECHST AG (DE) | 1999-09-01 | — | — | EP | disclosed |
| US-5602146-A | ANTIVIRAL AGENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| EP-0579968-A1 | 4-Iminoquinolines, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-26 | — | — | EP | disclosed |