Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882340 | 1.00 | TRPV1 (0.50) | TRPV1ACHEPTGESALOX5PTGS1 | |
| SCHEMBL8881800 | 0.86 | MAOB (0.55) | TRPV1PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL8881795 | 0.86 | MAOB (0.55) | TRPV1PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL16804151 | 0.81 | MAOB (0.62) | PTGESALOX5PTGS1PTGS2CTSL | |
| SCHEMBL4652315 | 0.81 | MAOB (0.63) | ACHEPTGESPTPN1MAOB | |
| SCHEMBL4652309 | 0.81 | MAOB (0.63) | ACHEPTGESPTPN1MAOB | |
| SCHEMBL15970448 | 0.80 | PTPN1 (0.57) | TRPV1APPPTPN1BACE1MAOB | |
| SCHEMBL14248732 | 0.80 | PTPN1 (0.57) | TRPV1APPPTPN1BACE1MAOB | |
| SCHEMBL15970447 | 0.80 | PTPN1 (0.57) | TRPV1APPPTPN1BACE1MAOB | |
| SCHEMBL15970225 | 0.80 | PTPN1 (0.57) | TRPV1APPPTPN1BACE1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | claimed |