Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | INHA | P05111 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.53 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.53 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15970225 | 1.00 | PTPN1 (0.57) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL15970447 | 1.00 | PTPN1 (0.57) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL15970448 | 1.00 | PTPN1 (0.57) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL14248573 | 0.98 | PTPN1 (0.55) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL14248571 | 0.98 | PTPN1 (0.55) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL8881800 | 0.83 | MAOB (0.55) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL8881795 | 0.83 | MAOB (0.55) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL1291989 | 0.83 | XDH (0.59) | BACE1CNR1PPARGTRPA1SLC6A2 | |
| SCHEMBL28252862 | 0.82 | PPARG (0.57) | PTPN1BACE1TRPV1CNR1CNR2 | |
| SCHEMBL4567342 | 0.81 | PTPN1 (0.74) | PTPN1BACE1TRPV1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464016-B2 | Catechol derivatives for treatment of oxidative stress diseases | EDISON PHARMACEUTICALS, INC. (US) | 2016-10-11 | — | — | US | disclosed |
| US-20140243424-A1 | CATECHOL DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| EP-2720689-A1 | CATECHOL DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | Edison Pharmaceuticals, Inc. (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2012174286-A1 | CATECHOL DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2012-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243424-A1 | CATECHOL DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | OPA1, PC, PCK2 | PTPN1 3919/4885BACE1 769/4885TRPV1 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.