Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228415 | 0.92 | ALDH1A1 (0.58) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9233359 | 0.92 | POLB (0.54) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL8883321 | 0.87 | POLB (0.49) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL8880097 | 0.86 | CYP3A4 (0.43) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9233103 | 0.85 | POLB (0.58) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9228345 | 0.85 | POLB (0.52) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL19779269 | 0.80 | POLB (0.55) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9234156 | 0.80 | ALDH1A1 (0.58) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL8881815 | 0.79 | CYP2D6 (0.48) | ALDH1A1MEN1KMT2AOPRM1CYP3A4 | |
| SCHEMBL18123311 | 0.79 | POLB (0.65) | POLBGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677316-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |