Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882701 | 1.00 | MEN1 (0.50) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8880594 | 1.00 | MEN1 (0.50) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8883714 | 1.00 | MEN1 (0.50) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL966853 | 0.97 | KMT2A (0.53) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL14735698 | 0.89 | MAPT (0.46) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8882089 | 0.88 | GAA (0.44) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8808599 | 0.88 | SMPD1 (0.45) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8810909 | 0.88 | SMPD1 (0.45) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8810764 | 0.88 | SMPD1 (0.45) | MEN1KMT2ASMPD1GAAMAPT | |
| SCHEMBL8806156 | 0.88 | SMPD1 (0.45) | MEN1KMT2ASMPD1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |