Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.71 |
| ▸ | FBP1 | P09467 | 2/20 | 0.69 |
| ▸ | VCP | P55072 | 1/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604120 | 1.00 | NFE2L2 (0.71) | NFE2L2FBP1VCPCYP19A1MAPT | |
| Formaldehyde SCHEMBL28045420 | 0.96 | NFE2L2 (0.67) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL15498134 | 0.88 | NFE2L2 (0.89) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL11301072 | 0.85 | CYP19A1 (0.93) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL11301074 | 0.85 | CYP19A1 (0.93) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL453450 | 0.85 | NFE2L2 (0.65) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL1405312 | 0.83 | NFE2L2 (1.00) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL1405314 | 0.83 | NFE2L2 (1.00) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL6159265 | 0.82 | NFE2L2 (0.57) | NFE2L2FBP1VCPCYP19A1MAPT | |
| SCHEMBL13622504 | 0.82 | NFE2L2 (0.79) | NFE2L2FBP1VCPCYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529683-B | The preparation method of 1-phenylpropene derivatives | 陕西师范大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-101048414-B | Fused tricyclic derivatives for the treatment of psychotic disorders | GLAXO GROUP LTD | 2011-09-07 | — | — | CN | disclosed |
| CN-101048414-A | Fused tricyclic derivatives for the treatment of psychotic disorders | GLAXO GROUP LTD (GB) | 2007-10-03 | — | — | CN | disclosed |
| US-5696110-A | ANTIULCER AGENTS | MERCK, SHARP & DOHME, LTD. (GB) | 1997-12-09 | — | — | US | disclosed |
| EP-0609306-A1 | BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF CHOLECYSTOKININ AND/OR GASTRIN RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |
| CN-1087086-A | Thiazolylvinylphenyl derivatives | HOFFMANN LA ROCHE (CH) | 1994-05-25 | — | — | CN | disclosed |
| WO-1993008176-A1 | BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF CHOLECYSTOKININ AND/OR GASTRIN RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539170-A1 | Benzodiazepine derivatives and their use as antagonists of cholecystokinin and/or gastrin receptors | MERCK SHARP & DOHME LTD. (GB) | 1993-04-28 | — | — | EP | disclosed |
| EP-0104863-B1 | LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |