Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | COMT | P21964 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | PTPRJ | Q12913 | 1/20 | 0.52 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883998 | 0.99 | ENPP2 (0.60) | ENPP2COMTKDM4ECYP1A2HIF1A | |
| SCHEMBL8882696 | 0.97 | ENPP2 (0.58) | ENPP2COMTKDM4ECYP1A2HIF1A | |
| SCHEMBL8882697 | 0.85 | KDM4E (0.53) | ENPP2COMTKDM4EHSD17B10PTPN7 | |
| SCHEMBL4461500 | 0.82 | COMT (0.64) | ENPP2COMTCYP1A2HIF1AHPGD | |
| SCHEMBL28463407 | 0.81 | KDM4E (0.74) | KDM4EHIF1AHPGDHSD17B10ALOX15 | |
| SCHEMBL9818532 | 0.80 | HSP90AA1 (0.66) | ENPP2COMTCYP1A2HIF1AHPGD | |
| 8-Hydroxy-7-Iodo-5-Quinolinesulfonic Acid SCHEMBL27581572 | 0.78 | HIF1A (0.56) | ENPP2COMTKDM4ECYP1A2HIF1A | |
| SCHEMBL2981945 | 0.78 | COMT (0.66) | ENPP2COMTKDM4ECYP1A2HIF1A | |
| SCHEMBL22802119 | 0.78 | COMT (0.67) | ENPP2COMTKDM4ECYP1A2HIF1A | |
| SCHEMBL13921640 | 0.78 | COMT (0.66) | ENPP2COMTCYP1A2HIF1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681832-A | FOR TREATMENT OF VIRAL DISEASES BY SUPPRESSING REPLICATION OF RETROVIRUSES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996025399-A1 | NOVEL AROYLANILINE DERIVATIVES, COMPOSITIONS AND USES THEREOF IN THE TREATMENT OF VIRAL INFECTIONS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-22 | — | — | WO | disclosed |